Mikio Shiozawa, from the Department of Surgery at Jichi Medical University, describes the development of sentinel lymph node biopsy using magnetic fluid (RESOVIST®):“Since around 2007, I had been working at a small community hospital that did not have the facilities to perform the radioisotope method and I was contemplating alternative ways, like using magnetic fluids.… Read More »
From 1999 to 2002, a third phase of multicenter clinical trials, focusing on axillary lymph node dissection (ALND), was conducted: randomized comparisons between “ALND vs. omission of ALND” and “ALND vs. radiotherapy” were performed, analyzing their respective disease-free survival rate, overall survival rate and lymph node recurrence rate, including sentinel node-negative and sentinel node-positive cases.The… Read More »
The concept of sentinel lymph nodes (SLN) was introduced in breast cancer treatment in the 1990s. The clinical trials conducted included identification of the sentinel lymph node through injection of radiocolloids and dyes near the tumor, subsequent dissection of the axillary lymph nodes, and examination for metastasis. Furthermore, correlations between presence or absence of metastasis… Read More »
TAKUMI, the handheld magnetic probe by Matrix Cell Research Institute Inc., was developed under collaborative research with the University of Tokyo and a team of renowned surgeons, aiming to achieve an alternative to conventional radioisotope techniques; a device that is both user- and patient-friendly, portable, minimally invasive and can be utilized even by medical institutions… Read More »
The permanent magnet utilized in TAKUMI, the handheld magnetic probe developed by Matrix Cell Research Institute Inc. to locate sentinel lymph nodes during breast cancer lumpectomy, provides many benefits, but what is a “permanent magnet”? Permanent magnetism was first discovered in Ancient Greece in 600 BC and is thus far older than Ampere’s law, which… Read More »