The concept of sentinel lymph nodes (SLN) was introduced in breast cancer treatment in the 1990s. The clinical trials conducted included identification of the sentinel lymph node through injection of radiocolloids and dyes near the tumor, subsequent dissection of the axillary lymph nodes, and examination for metastasis. Furthermore, correlations between presence or absence of metastasis in sentinel lymph nodes vs. non-sentinel lymph nodes was analyzed and followed by a number of clinical trials, whose meta-analyses showed that sentinel node identification was 96%, with a false negative rate of 7%.
TAKUMI handheld magnetic probe’s clinical trials were carried out in cooperation with renowned surgeons and proved that the sentinel lymph node identification rate is on par with the above results.